How mass spectrometer is used in radioactive hookup
Historically the success of mass spectrometry in the clinical laboratory has focused on drugs of abuse confirmations, newborn screening, and steroid analysis. Clinical applications of mass spectrometry continue to expand, and mass spectrometry is now being used in almost all areas of laboratory medicine. A brief background of the evolution of mass spectrometry in the clinical laboratory is provided with a discussion of future applications. Prominent examples of mass spectrometry are covered to illustrate how it has improved the practice of medicine and enabled physicians to provide better patient care. With increasing economic pressures and decreasing laboratory test reimbursement, mass spectrometry testing has been shown to provide cost-effective solutions. In addition to pointing out the numerous benefits, the challenges of implementing mass spectrometry in the clinical laboratory are also covered.
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An easy-to-understand explanation of how a mass spectrometer works, Diagram showing the five key processes at work in a typical mass spectrometer. Photo: A mass spectrometer being used to find the nitrogen content of what are termed CBRNE (chemical, biological, radiological, nuclear, and. A simple description of how a mass spectrometer works. ion mass spectrometers, although they use a different ionisation technique. In the last diagram, ion stream A is most deflected - it will contain ions with the smallest mass/charge ratio.
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Mass spectrometers consist of four basic parts; a handling system to introduce the unknown sample into the equipment; an ion source, in which a beam of particles characteristic of the sample is produced; an analyzer that separates the particles according to mass; and a detector, in which the separated ion components are collected and characterized. The essential principle of time-of-flight mass spectrometry is that all ions are accelerated to the same kinetic energy. Their velocities are inversely proportional to the square roots of their masses. The lighter ions of high velocity arrive at the detector earlier than the heavier ions of low velocity.